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Elanco Credelio Information

Tough flea & tick protection that works hard all month long. Credelio™ (lotilaner) and Credelio™ Cat (lotilaner);
Not actual size.

Fast-Acting Flea and Tick Protection For Dogs and Cats

Credelio (lotilaner) & Credelio CAT (lotilaner) are small chewable tablets that work hard to treat and prevent flea infestations, and treat and control tick infestations* all month long.

*Credelio CAT treats and controls Ixodes scapularis ticks

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Effective, Easy to Give, Targeted Power

Credelio & Credelio CAT aren't just gentle on your pet, it also kills ticks and fleas fast1,2 and lasts a full month. Credelio’s active ingredient, lotilaner, is a member of the isoxazoline family, a novel class of parasiticides that targets nerve receptors of ticks and fleas for powerful protection.3

Speed Of Kill

In dogs, Credelio starts killing ticks and fleas in just 4 hours (98.7% killed within just 8 hours) and, in cats, Credelio CAT starts killing within 6 hours (98% of ticks* and fleas killed within 12 hours).1,2

*Ixodes scapularis
Credelio™ (lotilaner)

Dosage Options for Dogs

  • 4.4 - 6.0 lbs
  • 6.1 - 12.0 lbs
  • 12.1 - 25.0 lbs
  • 25.1 - 50.0 lbs
  • 50.1 - 100.0 lbs
Credelio™ CAT (lotilaner)

Dosage Options for Cats

  • 2.0 - 4.0 lbs
  • 4.1 - 17.0 lbs

Details

Credelio & Credelio CAT are prescription tick and flea protection, available in a small, tasty chewable that's approved for dogs and cats.

For Dogs: Credelio kills adult fleas and is indicated for the treatment and prevention of flea infestations and treatment and control of tick infestations (lone star tick, American dog tick, black-legged tick and brown dog tick) for one month in dogs and puppies 8 weeks and older and 4.4 pounds or greater.

For Cats: Credelio CAT kills adult fleas and is indicated for the treatment and prevention of flea infestations for one month in cats and kittens 8 weeks of age and older and weighing 2 pounds or greater. It is also indicated for the treatment and control of black-legged tick infestations for one month in cats and kittens 6 months of age and older and weighing 2 pounds or greater.

Instructions

Credelio
One chewable tablet per month.

Credelio CAT
One chewable tablet per month.

Ingredients

Credelio: lotilaner

Credelio CAT: lotilaner

Credelio™ Indications
Credelio kills adult fleas and is indicated for the treatment and prevention of flea infestations and treatment and control of tick infestations (lone star tick, American dog tick, black-legged tick and brown dog tick) for one month in dogs and puppies 8 weeks and older and 4.4 pounds or greater.

Credelio™ Important Safety Information
Lotilaner is a member of the isoxazoline class of drugs. This class has been associated with neurologic adverse reactions including tremors, incoordination and seizures. Seizures have been reported in dogs receiving this class of drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. The safe use of Credelio in breeding, pregnant or lactating dogs has not been evaluated. The most frequently reported adverse reactions are weight loss, elevated blood urea nitrogen, increased urination and diarrhea. For complete safety information, please see Credelio product label or ask your veterinarian.

Credelio™ CAT Indications
Credelio CAT kills adult fleas and is indicated for the treatment and prevention of flea infestations for one month in cats and kittens 8 weeks of age and older and weighing 2 pounds or greater.

Credelio CAT is also indicated for treatment and control of black-legged tick infestations for one month in cats and kittens 6 months of age and older and weighing 2 pounds or greater.

Credelio™ CAT Important Safety Information
Lotilaner is a member of the isoxazoline class of drugs. This class has been associated with neurologic adverse reactions including tremors, incoordination and seizures. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Use with caution in cats with a history of neurologic disorders. The safety of Credelio CAT has not been established in breeding, pregnant and lactating cats. The effectiveness of Credelio CAT against black-legged ticks in kittens less than 6 months of age has not been evaluated. The most frequently reported adverse reactions are weight loss, rapid breathing and vomiting. For complete safety information, please see Credelio CAT product label or ask your veterinarian.

Frequently Asked Questions

Credelio has a rapid onset of action and begins to kill fleas on dogs in just 4 hours. In cats, Credelio CAT begins killing fleas in just 6 hours. In a well‑controlled laboratory study, Credelio demonstrated 100% effectiveness against adult fleas within 12 hours (24 hours for cats) after administration or infestation and lasted for up to 35 days.

Credelio starts to kill ticks (Ixodes ricinus) within 4 hours of administration, with 98.7% of ticks killed within 8 hours.2

Not at all. Credelio and Credelio CAT kill adult fleas quickly and effectively when used monthly according to label directions.

If there are fleas in your pet’s environment, it can take up to 6 weeks for flea larvae to emerge and grow into adults. Credelio and Credelio CAT kill adult fleas before they can lay eggs. If you see fleas on your pet, they are most likely new adult fleas that will die very quickly.

All animals in the household should be treated with an approved flea product to minimize the likelihood of flea re-infestation. It may also be necessary to apply an approved flea treatment product to your carpet and furniture to remove the presence of fleas in your dog’s or cat’s environment.

Maintain consistent monthly administration of Credelio or Credelio CAT to provide continual flea protection in your pet.

For dogs, the small and tasty beef-flavored monthly chewable tablet was accepted and tolerated by the 70 different dog breeds that were tested, including Chihuahuas and Yorkshire Terriers.3

In a field trial, the acceptability of Credelio was tested at 10 different locations across the U.S., and 94% of dogs accepted Credelio from the hand, in the bowl or with food.3 The remaining 6% accepted Credelio when placed in the mouth. There were no reports of unsuccessful dosing.

In cats, the chewable tablet was designed to be small and easy to give, with a flavor and smell that cats find appealing.

In real-world testing, cat owners successfully administered 99.5% of tablets to their cats. 46.9% of cats ate Credelio CAT on their own when offered by hand, placed in an empty food bowl or with food. 52.6% of cats successfully took the pill when placed in the mouth.

Yes, Credelio and Credelio CAT are only available with a prescription from your veterinarian.

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Powered by Costco Health Solutions. Costco Member Prescription Program (CMPP) is a direct-to-members savings program administered by Costco Health Solutions, Inc. and Ventegra Inc. Participating pharmacies are subject to change without notice and are not available in all areas. CMPP is not insurance or intended as a replacement for insurance. Claims submitted for coverage under publicly funded programs (e.g. Medicare, Medicaid, etc.) or private insurance are not eligible for CMPP participation. Costco Health Solutions, Inc. 845 Lake Drive Issaquah, WA 98027 https://www.costcohealthsolutions.com/.

References:

  1. Cavalleri D. et al 2017. "Assessment of the speed of flea kill of lotilaner (Credelio™) throughout the month following oral administration to dogs." Parasites & Vectors. 10:529.
  2. Murphy M. et al 2017. "Laboratory evaluation of the speed of kill of lotilaner (Credelio™) against Ixodes ricinus ticks on dogs." Parasites & Vectors. 10:541.
  3. Elanco Animal Health. Data on file.